Serotyping (heat stable antigens) was performed on 398 strains of Campylobacter jejuni from faeces of human enteritis cases in England.
Strains isolated over 12 months at three locations were heterogeneous with 33 HS serotypes represented.
HS I and HS4 complex were the predominant types (34% of all strains).
The monthly strain frequency distributions were similar at the three locations.
The late spring peak appeared to be associated with a rise in miscellaneous serotypes rather than with the emergence of any characteristic predominant serotype.
PFGE DNA restriction profiling provided evidence of a high degree of genomic diversity within the common HS I and HS4 complex serotypes, irrespective of the geographical source, yet some subtypes were common to more than one location.
The study showed that C.
Jejuni strain subtypes from human enteric infections in England were highly diverse, and that HS serotyping must be combined with a more discriminatory subtyping method such as PFGE DNA profiling to provide an accurate basis for epidemiological surveillance.
Mots-clés Pascal : Diarrhée, Campylobactériose, Bactériose, Infection, Campylobacter jejuni, Campylobacteraceae, Bactérie, Sérotypie, Homme, Angleterre, Grande Bretagne, Royaume Uni, Europe, Isolement, Electrophorèse champ pulsé, Identification, Epidémiologie moléculaire, Appareil digestif pathologie, Intestin pathologie
Mots-clés Pascal anglais : Diarrhea, Campylobacter infection, Bacteriosis, Infection, Campylobacter jejuni, Campylobacteraceae, Bacteria, Serotyping, Human, England, Great Britain, United Kingdom, Europe, Isolation, Pulsed field electrophoresis, Identification, Molecular epidemiology, Digestive diseases, Intestinal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0548731
Code Inist : 002B05B02F. Création : 24/03/1998.