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  1. Community-based urine screening for Chlamydia trachomatis with a ligase chain reaction assay.

    Article - En anglais

    Background 

    Urine tests for Chlamydia trachomatis permit expansion of screening beyond traditional clinic environments.

    Prevention of infection in teenagers is a high priority.

    Objective 

    To define the prevalence of C. trachomatis among teenagers by using the ligase chain reaction assay on urine specimens and to evaluate leukocyte esterase testing of urine specimens as an indicator of infection.

    Design 

    Cross-sectional study.

    Setting 

    An adolescent clinic, a juvenile detention facility, seven school-based clinics, and three community-based youth organizations in Seattle, Washington.

    Participants 

    10 118 sexually active teenagers and young adults.

    Measurements 

    Chlamydia trachomatis infection detected in urine specimens by ligase chain reaction assay and leukocyturia detected by leukocyte esterase testing.

    Results 

    The prevalence of chlamydial infection among female participants was 8.6% and declined with increasing age ; among male participants, it was 5.4% and increased with increasing age.

    In female participants, independent predictors of infection were being 17 years of age or younger (odds ratio [OR], 1.49), having had two or more sex partners in the previous 2 months (OR, 1.61), and having genitourinary symptoms (OR, 1.46).

    In male participants, independent predictors were being of nonwhite race or ethnicity (OR, 2.00 to 3.08), having had two or more sex partners in the previous 2 months (OR, 1. (...)

    Mots-clés Pascal : Chlamydia trachomatis, Chlamydiaceae, Chlamydiales, Bactérie, Prévalence, Communauté, Ligases, Enzyme, Réaction chaîne, Exploration bactériologique, Urine, Diagnostic, Etude transversale, Adolescent, Homme, Maladie sexuellement transmissible, Prévention, Bactériose, Infection, Appareil urinaire pathologie, Activité biologique

    Mots-clés Pascal anglais : Chlamydia trachomatis, Chlamydiaceae, Chlamydiales, Bacteria, Prevalence, Community, Ligases, Enzyme, Chain reaction, Bacteriological investigation, Urine, Diagnosis, Cross sectional study, Adolescent, Human, Sexually transmitted disease, Prevention, Bacteriosis, Infection, Urinary system disease, Biological activity

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0547265

    Code Inist : 002B05B02G. Création : 24/03/1998.