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  1. Functional disability before myocardial infarction in the elderly as a determinant of infarction severity and postinfarction mortality.

    Article - En anglais


    Functional disability is a common condition among elderly patients.

    However, to our knowledge, its effect on outcome of myocardial infarction (MI) has not been assessed.

    Our objectives were to determine whether disability in the activities of daily living measured before Ml is a predictor of Ml severity and mortality.


    Disability in activities of daily living was measured prospectively in a cohort of 222 patients who were hospitalized with acute Ml.

    Outcome measures were severity characteristics on admission to the hospital (higher Killip class, presence of new Q waves in the first electrocardiogram, and lower systolic blood pressure), and 6-month mortality.


    Patients with disability before hospitalization were older and had more comorbidity.

    After adjusting for these factors and for delay in hospital arrival, disability was still significantly associated with clinical severity on admission to the hospital and with mortality (adjusted relative risk of death for patients with disability vs patients without disability, 2.01 ; 95% confidence interval, 1.23-3.28).

    Clinical severity and hospital treatment explained the higher mortality of patients with disability.

    When these factors were added to the previous model, the relative risk of mortality for patients with disability vs patients without disability was 1.24, and the 95% confidence interval was 0.73 to 2.12. (...)

    Mots-clés Pascal : Infarctus, Myocarde, Trouble fonctionnel, Mouvement corporel, Valeur prédictive, Indice gravité, Evolution, Mortalité, Etude statistique, Vieillard, Homme, Appareil circulatoire pathologie, Cardiopathie coronaire, Myocarde pathologie

    Mots-clés Pascal anglais : Infarct, Myocardium, Dysfunction, Body movement, Predictive value, Severity score, Evolution, Mortality, Statistical study, Elderly, Human, Cardiovascular disease, Coronary heart disease, Myocardial disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0543302

    Code Inist : 002B12A03. Création : 24/03/1998.