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  1. Impacting cost and appropriateness of stress ulcer prophylaxis at a university medical center.

    Article - En anglais


    To determine the appropriateness and medication cost of stress ulcer prophylaxis before and after a targeted educational intervention.


    In the preintervention cohort (phase 1), 264 patients were evaluated over 2 months, using stress ulcer prophylaxis guidelines developed by a comprehensive literature search.

    Targeted educational programs were subsequently used to inform trauma housestaff on appropriate usage of stress ulcer prophylaxis medications with emphasis on using sucralfate.

    The postintervention cohort (phase 2) involved concurrent evaluation of 279 patients.

    Length of inappropriate stress ulcer prophylaxis (i.e., did not meet approved guidelines) between phases was compared using a Student's t-test for independent samples (a=05).


    A 365-bed university medical center.


    Patients admitted to any of the intensive care units and all patients who were placed on histamine-2-antagonists or sucralfate for stress ulcer prophylaxis.


    Educational intervention regarding appropriate stress ulcer prophylaxis directed at the trauma service.

    Measurements and Main Results 

    Patient demographics in the two phases were similar and there was no difference in the number of patient risk factors for stress-induced bleeding.

    The mean length of inappropriate stress ulcer prophylaxis was 5.78 ± 4.36 days in phase 1 and 4.66 ± 3.10 days in phase 2 (p<. 05). (...)

    Mots-clés Pascal : Soin intensif, Ulcère, Gastroduodénal, Stress, Complication, Prévention, Programme enseignement, Médecin, Analyse coût, Evaluation, Homme, Etude comparative, Economie santé, Appareil digestif pathologie, Estomac pathologie, Intestin pathologie, Personnel sanitaire

    Mots-clés Pascal anglais : Intensive care, Ulcer, Gastroduodenal, Stress, Complication, Prevention, Educational program, Physician, Cost analysis, Evaluation, Human, Comparative study, Health economy, Digestive diseases, Gastric disease, Intestinal disease, Health staff

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0542641

    Code Inist : 002B27B15. Création : 24/03/1998.