logo BDSP

Base documentaire

  1. Clinical utility of hygroscopic heat and moisture exchangers in intensive care patients.

    Article - En anglais


    To compare the degree of bacterial circuit colonization, frequency of ventilator-associated pneumonia (VAP), character of respiratory secretions, rewarming of hypothermic patients, disposable costs, and air flow resistance in intensive care patients ventilated using either a heat and moisture exchanger (HME) or hot water (HW) humidifier circuit.


    A prospective, randomized blinded trial of patients in the intensive care unit undergoing mechanical ventilation.


    A metropolitan teaching hospital.


    One hundred sixteen patients undergoing mechanical ventilation for a minimum period of 48 hrs were enrolled.


    Patients were randomized to three ventilation groups using a) an HW circuit with a 2-day circuit change (n=41) ; or b) a bacterial-viral filtering HME in the circuit, with either a 2-day (n=42) ; or c) a 4-day circuit change (n=33).

    Measurements and Main Results 

    Circuit colonization was assessed using quantitative culture of washings taken from the circuit tubing and semiquantitative culture of swabs from the Y connectors.

    Sixty-seven percent of HW circuits became contaminated compared with 12% in the two HME groups (p<. 0001).

    Median colony counts were lower in the HME groups (p<. 0001).

    If circuits at first circuit change were contaminated in the HW group, 89% of subsequent circuit changes became contaminated compared with 0% and 25% for the 2-and 4-day HME groups, respectively. (...)

    Mots-clés Pascal : Ventilation mécanique, Ventilateur, Filtre, Echangeur chaleur, Humidité, Etude comparative, Evaluation performance, Appareillage, Homme, Analyse coût, Economie santé, Ventilation artificielle, Soin intensif

    Mots-clés Pascal anglais : Mechanical ventilation, Fan, Filter, Heat exchanger, Humidity, Comparative study, Performance evaluation, Instrumentation, Human, Cost analysis, Health economy, Artificial ventilation, Intensive care

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0542582

    Code Inist : 002B27B14D. Création : 24/03/1998.