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  1. The life-time rates of three major mood disorders and four major anxiety disorders in alcoholics and controls.

    Article - En anglais


    While psychiatric symptoms are common in the general population and even more prevalent in alcoholics, their clinical implications are not clear.

    The goal of this study was to establish the life-time rates of several independent and concurrent mood and anxiety disorders in alcoholics, controls and their relatives.


    Structured interviews were administered to alcoholics entering treatment, their relatives, and controls.


    The study was carried out in six different centers in the United States as part of the Collaborative Study on the Genetics ofAlcoholism (COGA).


    Data were gathered from 2713 alcohol dependent subjects (probands and their alcoholic relatives) and 919 controls.


    The timeline-based Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) interview was administered face to face by trained, closely supervised interviewers.

    The life-time rates for concurrent and independent disorders were determined for three DSM-III-R major mood and four major anxiety disorders.


    Some form of independent mood disorder was seen during the life-time in slightly fewer alcoholics than controls (14.0% and 17.1%), but alcoholics did show higher rates of independent bipolar disorder (2.3% vs. 1.0%). The life-time rate for independent anxiety disorders was significantly higher in alcoholics than controls (9.4% vs. 3.7%), with most of the differential related to panic disorder (4. 2% vs. 1.0%) and social phobia. (...)

    Mots-clés Pascal : Alcoolisme, Dépendance, Association morbide, Trouble humeur, Trouble anxieux, Epidémiologie, Homme

    Mots-clés Pascal anglais : Alcoholism, Dependence, Concomitant disease, Mood disorder, Anxiety disorder, Epidemiology, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0541426

    Code Inist : 002B18C05B. Création : 24/03/1998.