Objectives This study examined mortality from nonmalignant respiratory diseases among ferroalloy workers.
Methods The cohort comprised 14 730 men employed for the first time in 1933-1990 and for at least 6 months in 1 of 12 plants.
The duration of work in specific departments and exposure to amorphous silica in the ferrosilicon/silicon-metal (FeSi/Si-met) plants, estimated from a job-exposure matrix, were the main exposure variables.
Deaths were observed during 1962-1990.
The mortality was analyzed with the use of standardized mortality ratios (SMR) and internal comparisons of rates.
Results Overall mortality from nonmalignant respiratory diseases was not increased, but mortality from bronchitis, emphysema, and asthma combined was significantly increased among the men with at least 3 years of FeSi/Si-met furnace work (SMR 1.82,16 deaths).
A Poisson regression analysis of the mortality from these causes among 6359 employees in the FeSi/Si-met plants showed a significant increase of 0.06 per unit of amorphous silica exposure observed 10-20 years after the exposure.
Six men died of pneumonia while still employed in a ferromanganese/silicomanganese (FeMn/SiMn) plant.
No corresponding deaths occurred among employees in FeSi/Si-met plants.
Only 2 deaths from pneumoconiosis were observed in the total cohort.
Conclusions Among employees in FeSi/Si-met plants increased mortality from bronchitis, emphysema, and asthma may be associated with previous exposure to amorphous silica. (...)
Mots-clés Pascal : Appareil respiratoire pathologie, Exposition professionnelle, Toxicité, Fer Silicium, Manganèse Silicium, Industrie métallurgique, Ferroalliage, Ferromanganèse, Mortalité, Epidémiologie, Médecine travail, Homme, Norvège, Europe
Mots-clés Pascal anglais : Respiratory disease, Occupational exposure, Toxicity, Iron Silicon, Manganese Silicon, Metallurgical industry, Ferro alloy, Ferromanganese, Mortality, Epidemiology, Occupational medicine, Human, Norway, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0539689
Code Inist : 002B03L05. Création : 24/03/1998.