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  1. Breast cancer risk and alcohol consumption : Results from a large case-control study.

    Article - En anglais


    Alcohol use is associated with breast cancer in many epidemiological studies.

    Most, however, have measured risk from recent consumption patterns, and only a few include analyses for duration of drinking or age that a woman started to drink.

    The authors studied the effect of these variables, as well as of recent alcohol consumption patterns, on breast cancer risk.


    Data from a large case-control study conducted in Long Island, New York from 1 January 1984 to 31 December 1986 were used.

    A total of 1214 women aged 20-79 years with incident breast cancer were interviewed.

    A control was selected for each case from driver's license files, and matched on age and county of residence.

    Alcohol consumption was measured as 

    Ever versus never, grams of alcohol per day, age started drinking, and total years drinking.


    After adjustment for breast cancer risk factors, the odds ratio for ever versus never drinking was 1.40 (95% confidence interval [Cl] 1.09-1.79) ; odds ratios for>0-5 and =5 grams of alcohol use per day, as compared to non-drinkers, were 1.29 (95% Cl : 1.00-1.65) and 1.46 (95% Cl : 1.13-1.89), respectively.

    Age when drinking began was not related to breast cancer risk, but the greater the total years of drinking, up to 40 years (odds ratio 1.48,95% Cl : 1.13-1.93), the greater the risk.

    However, when grams per day and duration of drinking were simultaneously included in the multivariate model, duration was not important as a risk factor. (...)

    Mots-clés Pascal : Tumeur maligne, Glande mammaire, Consommation, Boisson alcoolisée, Epidémiologie, Facteur risque, Femme, Homme, Etude cas témoin, Etats Unis, Amérique du Nord, Amérique, Glande mammaire pathologie

    Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Consumption, Alcoholic beverage, Epidemiology, Risk factor, Woman, Human, Case control study, United States, North America, America, Mammary gland diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0534244

    Code Inist : 002B20E02. Création : 13/02/1998.