Sexual risk behavior and risk factors for HIV-1 seroconversion in homosexual men participating in the Tricontinental Seroconverter Study, 1982-1994.
Trends in sexual behavior associated with incident infection with human immunodeficiency virus (HIV) type 1 are described and a case-control study was conducted to examine risk factors for HIV seroconversion in homosexual men who became infected with HIV between 1982 and 1994 from four geographic sites :
Amsterdam, the Netherlands ;
Changes in sexual behaviors were evaluated from cohort visits in the preseroconversion, seroconversion, and post-seroconversion intervals and were further examined over three time periods : 1982-1984,1985-1987, and 1988-1994.
In a case-control study, sexual behaviors, substance use, and presence of sexually transmitted disease were compared between 345 HIV-positive cases and 345 seronegative controls matched by visit date and site.
Receptive anal intercourse was the sexual behavior most highly associated with seroconversion.
The odds ratio (OR) per receptive anal intercourse partner increase was 1.05 (95% confidence interval (Cl) 1.02-1.09).
To more carefully examine risk associated with receptive oral intercourse, analyses were done in a subgroup of men who reported no or one receptive anal intercourse partner.
The risk (OR) associated with receptive oral intercourse partner increase was 1.05 (95% Cl 1.0-1.11).
In multivariate conditional logistic regression analyses, presence of sexually transmitted disease (OR=3.39,95% Cl 1.95-5.91) and amphetamine use (OR=2. (...)
Mots-clés Pascal : SIDA, Virose, Infection, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Comportement sexuel, Homosexualité, Epidémiologie, Facteur risque, Incidence, Evolution, Homme, Mâle, Etude multicentrique, International, Etude cas témoin, Immunopathologie, Immunodéficit, Sexualité
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Sexual behavior, Homosexuality, Epidemiology, Risk factor, Incidence, Evolution, Human, Male, Multicenter study, International, Case control study, Immunopathology, Immune deficiency, Sexuality
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0534157
Code Inist : 002B06D01. Création : 13/02/1998.