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  1. Recent policy and technical developments in biological monitoring in the United Kingdom.

    Article, Communication - En anglais

    International Symposium on Biological Monitoring in Occupational and Environmental Health. Espoo (FIN), 1996/09/11.

    Copyright (c) 1997 Elsevier Science B.V. All rights reserved.

    In 1996 the United Kingdom's Health and Safety Executive introduced biological monitoring guidance values for six substances, butoxyethanol, N, N-dimethylacetamide, lindane, methylene-bis (2-chloroaniline), mercury and methylenedianiline.

    These guidance values were set as either health-based values or hygiene-based values calculated according to the 90th percentile (benchmark concept).

    Recent technical developments from the Health and Safety Laboratory are described in this paper and include :

    • (i) the use of breath analysis as a useful non-in vasive routine monitoring technique ;

    • (ii) flow cytometry as a means for measuring different patterns of immune cell activation from workers exposed to respiratory sensitisers when compared with those exposed to chemical irritants ;

    • (iii) the use of molecular techniques to explore the possible role of individual susceptibility in the development and severity of glomerulonephritis ;

    • (iv) the development of expert systems for predicting the skin permeability of chemicals, and respiratory and skin sensitisation. 1997 Elsevier Science B.V.

    Mots-clés Pascal : Composé chimique, Surveillance biologique, Politique sanitaire, Royaume Uni, Europe, Recommandation, Hygiène, Système expert, Génétique, Prédisposition, Modélisation, Homme

    Mots-clés Pascal anglais : Chemical compound, Biological monitoring, Health policy, United Kingdom, Europe, Recommendation, Hygiene, Expert system, Genetics, Predisposition, Modeling, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0528861

    Code Inist : 002B03A. Création : 13/02/1998.