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  1. An investigation into neurologic and neurobehavioral effects of long-term agrichemical use among deciduous fruit farm workers in the Western Cape, South Africa.

    Article, Communication - En anglais

    International Symposium on Neurobehavioral Methods and Effects in Occupational and Environmental Health. Cairo (EGY), 1994/12/03.

    Long-term exposure to organophosphates (OPs) in the absence of acute poisoning is increasingly suspected of causing chronic neurologic and neurobehavioral effects.

    A cross-sectional survey of 163 spray operators on deciduous fruit farms in the Western Cape, South Africa, and 84 nonspraying labororers was conducted in 1993 to investigate the relationship between long-term OP exposures and neurological and neurobehavioral outcomes.

    The study also sought to evaluate the performance of a set of neurobehavioral test batteries based on the information-processing theory of cognitive psychology, relative to the more established World Health Organization's Neurobehavioral Core Test Battery (WHO NCTB).

    These information-processing tests were designed for use in studies of subjects with little education, which are frequently conducted in developing countries in agriculture.

    They draw on experience from a previous South African study in which problems were encountered with a lack of cross-cultural validity of conventional test batteries.

    No evidence was found of a relationship between long-term OP exposure and loss of vibration sense.

    Small associations were found with the NCTB Pursuit-Aiming and Santa Ana (nondominant hand) subtests.

    The overall evidence of neurologic and neurobehavioral effects of long-term OP exposure was small ; exposure misclassification may have contributed to this finding. (...)

    Mots-clés Pascal : Pesticide, Organophosphoré, Exposition professionnelle, Médecine travail, Agriculteur, Pulvérisation, Verger, Homme, République Sud Africaine, Afrique, Toxicité, Chronique, Etude transversale, Test neuropsychologique, Système nerveux pathologie

    Mots-clés Pascal anglais : Pesticides, Organophosphorus compounds, Occupational exposure, Occupational medicine, Farmer, Spraying, Orchard, Human, South Africa, Africa, Toxicity, Chronic, Cross sectional study, Neuropsychological test, Nervous system diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0527936

    Code Inist : 002B03G. Création : 13/02/1998.