International Symposium on Neurobehavioral Methods and Effects in Occupational and Environmental Health. Cairo (EGY), 1994/12/03.
Long-term exposure to organophosphates (OPs) in the absence of acute poisoning is increasingly suspected of causing chronic neurologic and neurobehavioral effects.
A cross-sectional survey of 163 spray operators on deciduous fruit farms in the Western Cape, South Africa, and 84 nonspraying labororers was conducted in 1993 to investigate the relationship between long-term OP exposures and neurological and neurobehavioral outcomes.
The study also sought to evaluate the performance of a set of neurobehavioral test batteries based on the information-processing theory of cognitive psychology, relative to the more established World Health Organization's Neurobehavioral Core Test Battery (WHO NCTB).
These information-processing tests were designed for use in studies of subjects with little education, which are frequently conducted in developing countries in agriculture.
They draw on experience from a previous South African study in which problems were encountered with a lack of cross-cultural validity of conventional test batteries.
No evidence was found of a relationship between long-term OP exposure and loss of vibration sense.
Small associations were found with the NCTB Pursuit-Aiming and Santa Ana (nondominant hand) subtests.
The overall evidence of neurologic and neurobehavioral effects of long-term OP exposure was small ; exposure misclassification may have contributed to this finding. (...)
Mots-clés Pascal : Pesticide, Organophosphoré, Exposition professionnelle, Médecine travail, Agriculteur, Pulvérisation, Verger, Homme, République Sud Africaine, Afrique, Toxicité, Chronique, Etude transversale, Test neuropsychologique, Système nerveux pathologie
Mots-clés Pascal anglais : Pesticides, Organophosphorus compounds, Occupational exposure, Occupational medicine, Farmer, Spraying, Orchard, Human, South Africa, Africa, Toxicity, Chronic, Cross sectional study, Neuropsychological test, Nervous system diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0527936
Code Inist : 002B03G. Création : 13/02/1998.