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  1. Peptic ulcer bleeding in the elderly : relative roles of Helicobacter pylori and non-steroidal anti-inflammatory drugs.

    Article - En anglais

    Background-Most ulcers are caused, one can deduce, by Helicobcter pylori or by use of non-steroidal anti-inflammatory drugs (NSAIDs).

    Whether both together are worse than one alone is something that is quite unknown.

    Aim-To study both factors in order to see whether they interact together positively.

    Method-A case control study of ulcer bleeding in elderly patients chosen without weeding.


    NSAID usage increased risk substantially.

    So did H pylori infection (but relative risk less than three).

    Neither seemed to interact.

    Their actions were discretely intact.

    Conclusion-H pylori effects ulcer bleeding in an adverse manner but does not make the risk of NSAIDs worse.

    Mots-clés Pascal : Ulcère, Gastroduodénal, Complication, Hémorragie, Gastrointestinal, Effet biologique, Gastrite, Campylobactériose, Bactériose, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Chimiothérapie, Antiinflammatoire non stéroïde, Epidémiologie, Vieillard, Homme, Appareil digestif pathologie, Estomac pathologie, Intestin pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Pharmacovigilance

    Mots-clés Pascal anglais : Ulcer, Gastroduodenal, Complication, Hemorrhage, Gastrointestinal, Biological effect, Gastritis, Campylobacter infection, Bacteriosis, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Chemotherapy, Non steroidal antiinflammatory agent, Epidemiology, Elderly, Human, Digestive diseases, Gastric disease, Intestinal disease, Cardiovascular disease, Vascular disease, Pharmacovigilance

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0523790

    Code Inist : 002B13B03. Création : 13/02/1998.