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  1. Human neurobehavioral research methods : Impact of subject variables.

    Article, Communication - En anglais

    International Symposium on Neurobehavioral Methods and Effects in Occupational and Environmental Health. Cairo (EGY), 1994/12/03.

    Behavioral tests are used in work site and community research to detect and characterize the effects of neurotoxic chemical exposures in human populations, but the influence of subject variables on test performance has not been well studied in normal adult populations.

    This research sought to evaluate the impact of two variables, education and cultural group, on 18 widely used tests of neurotoxic insult.

    Behavioral tests from the two consensus neurotoxicity test batteries (established by the World Health Organization and the U.S. Agency for Toxic Substances and Disease Registry) were administered to 715 people aged 26-45 with 0-18 years of education, drawn from European descent United States majority, American Indian, African American, and Latin American populations.

    Education, cultural group, age, and gender affected the outcome of behavioral tests as revealed by ANOVA, MANOVA, and multiple regression techniques.

    Education, followed by cultural group, accounted for the most variance in the tests studied.

    More importantly, years of education and cultural group had 13-25% shared variance on the cognitive tests and highly significant interactions derived from ANOVA tests.

    This suggests that these factors should be controlled in the design of a study rather than in the statistical analysis. (...)

    Mots-clés Pascal : Composé chimique, Toxicité, Système nerveux pathologie, Homme, Méthode étude, Test neuropsychologique, Milieu professionnel, Exposition professionnelle, Médecine travail, Statut culturel, Niveau étude, Comparaison interindividuelle, Age, Sexe

    Mots-clés Pascal anglais : Chemical compound, Toxicity, Nervous system diseases, Human, Investigation method, Neuropsychological test, Occupational environment, Occupational exposure, Occupational medicine, Cultural status, Education level, Interindividual comparison, Age, Sex

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0522983

    Code Inist : 002B03A. Création : 13/02/1998.