Zur Effizienz der Hepatitis B-Schutzimpfung.
Traduction en anglais : Efficiency of hepatitis B vaccination.
Health care workers are at increased hepatitis B risk.
In the course of a study with 5035 persons occupied at the Freiburg university hospital, efficacy of hepatitis B vaccination and duration of protection were investigated.
Estimations of post-vaccination-anti Hbs showed that women, younger persons, persons with a body mass index<25 and non-smokers had higher anti Hbs concentrations than men, elderly persons overweight persons and smokers. 2% of female and 1.5% of male vaccinees did not develop anti Hbs and 4.8% and 7.1%, respectively were low responders (anti Hbs<100<10 IU/l).
Estimations of vaccination efficacy revealed that even 10 years after basic immunisation at least 50% of all vaccinees should have anti Hbs concentrations>100 IU/l. The results of the study show that vaccination of children in accordance with German and WHO recommendations will afford full protection (anti Hbs>10 IU/l) at least 99% of all cases.
Mots-clés Pascal : Hépatite virale B, Virose, Infection, Vaccination, Activité professionnelle, Personnel sanitaire, Durée, Protection, Evaluation, Efficacité, Homme, Prévention, Risque, Médecine travail, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis B, Viral disease, Infection, Vaccination, Professional activity, Health staff, Duration, Protection, Evaluation, Efficiency, Human, Prevention, Risk, Occupational medicine, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0522394
Code Inist : 002B30B01B. Création : 13/02/1998.