The effect of age on cardiovascular risk factors in Chinese women.
Chinese women traditionally have a low incidence of coronary heart disease.
However, information on cardiovascular risk factors in this population are relatively scarce.
We examined these risk factors in 601 Hong Kong Chinese women (age±SEM, 38.5±0.4 years ; range, 18-66 years) stratified into four age groups (group 1, ¾30 years ; group 2,31-40 years ; group 3,41-50 years ; group 4, =51 years).
Increasing age in Chinese women was associated with increased body mass index, waist-to-hip ratio, systolic and diastolic blood pressure, fasting plasma total cholesterol, triglyceride, low-density lipoprotein, apolipoprotein B, fasting and 2-h plasma glucose, glycated haemoglobin, fasting plasma insulin and urate concentrations.
After adjustment for body mass index, waist-to-hip ratio and smoking, all these age-related associations remained statistically significant except for fasting plasma insulin concentration.
There was a progressive increase with age in the prevalence of glucose intolerance, hypertension, dyslipidaemia and obesity.
These prevalence rates further increased in subjects aged 51 years (the mean menopausal age in Asian women) or above.
These findings suggest that age had an important and independent effect on cardiovascular risk in Chinese women and that, as in Caucasians, the onset of menopause might further increase this risk.
Mots-clés Pascal : Cardiopathie coronaire, Hypertension artérielle, Hyperlipémie, Obésité, Ménopause, Mongoloïde, Epidémiologie, Facteur risque, Adulte, Homme, Age, Femelle, Chinois, Lipide, Etat nutritionnel, Appareil circulatoire pathologie, Métabolisme pathologie, Dyslipémie, Trouble nutrition
Mots-clés Pascal anglais : Coronary heart disease, Hypertension, Hyperlipemia, Obesity, Menopause, Mongoloid, Epidemiology, Risk factor, Adult, Human, Age, Female, Chinese, Lipids, Nutritional status, Cardiovascular disease, Metabolic diseases, Dyslipemia, Nutrition disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0522177
Code Inist : 002B12A03. Création : 13/02/1998.