Sexual and perinatal transmission of hepatitis C.
National Institutes of Health Consensus Development Conference. Bethesda (USA), 1997/03/24.
Such nonpercutaneous routes of hepatitis C virus (HCV) transmission as sexual and perinatal spread are relatively inefficient.
Several observations have been cited to support a role for sexual transmission of hepatitis C. Approximately 10% of persons with reported cases of acute hepatitis C in the United States report a history of potential sexual exposure.
Anecdotal cases of sexual transmission have been reported, and HCV nucleotide sequence homology has been observed in viral isolates from sexual partners.
Similarly, the prevalence of HCV infection is increased in groups with a high risk of exposure to sexually transmitted viral infections.
Other observations, however, weigh against sexual transmission of HCV infection.
Sexual transmission is negligible in sex-partner studies ; alternative risk factors account for many cases of apparent sexual transmission between sexual partners ; the prevalence of HCV infection in high-risk groups is much lower than that of other sexually transmitted infections ; and the risk of apparently sexually transmitted HCV infection does not always correlate with intensity and duration of sexual exposure.
The United States Public Health Service has estimated that the risk of sexual transmission is approximately 5%, well below the risk of sexual transmission of hepatitis B or human immunodeficiency virus (HIV). (...)
Mots-clés Pascal : Hépatite virale C, Virose, Infection, Contamination, Transmission mère enfant, Maladie sexuellement transmissible, Incidence, Milieu familial, Etude statistique, Homme, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis C, Viral disease, Infection, Contamination, Mother to child transmission, Sexually transmitted disease, Incidence, Family environment, Statistical study, Human, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0515877
Code Inist : 002B05C02G. Création : 13/02/1998.