National Institutes of Health Consensus Development Conference. Bethesda (USA), 1997/03/24.
In the United States, the annual number of newly acquired acute hepatitis C virus (HCV) infections has declined from an estimated 180,000 in the mid 1980s to an estimated 28,000 in 1995.
Approximately 25% to 30% of these infections are clinically apparent cases that are sufficiently symptomatic to gain medical attention.
Deaths from fulminant hepatitis C are rare.
The prevalence of antibody to HCV (anti-HCV) in the general population of the United States is 1.8%, corresponding to an estimated 3.9 million Americans infected with HCV, and an estimated 8,000 to 10,000 deaths each year result from HCV-associated chronic liver disease.
HCV infection affects persons of all ages, but most acute cases of hepatitis C and the highest prevalence of anti-HCV are found among young adults.
The highest proportion both of incident cases and prevalent infections is among whites, but the highest incidence and prevalence rates are among non-white racial/ethnic groups. in the past, transfusion of blood and blood products was an important source of HCV transmission, but currently, high-risk drug and sexual exposures account for most HCV transmission.
Although the incidence of acute hepatitis C has declined, there is a large reservoir of chronically infected Americans who can serve as a source of transmission to others and who are at risk of the severe consequences of chronic liver disease.
Mots-clés Pascal : Hépatite virale C, Virose, Infection, Virus hépatite C, Flaviviridae, Virus, Incidence, Prévalence, Facteur risque, Prévention, Epidémiologie, Homme, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis C, Viral disease, Infection, Hepatitis C virus, Flaviviridae, Virus, Incidence, Prevalence, Risk factor, Prevention, Epidemiology, Human, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0515876
Code Inist : 002B30A01A2. Création : 13/02/1998.