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  1. Dietary vitamin C and bone mineral density in postmenopausal women in Washington State, USA.

    Article - En anglais

    Study objective-To examine the relationship between dietary vitamin C and hip bone mineral density (BMD) in postmenopausal women.

    Design-This was a cross sectional study using retrospective diet and vitamin supplement data.

    Setting-The Seattle area of Washington State.

    Participants-Screenees for a clinical trial of a drug to prevent osteoporotic fractures ; 1892 women aged 55-80 years who had hip bone densitometry and osteoporosis risk factor information.

    Main results-Mean energy adjusted dietary intake of vitamin C was 113 mg/day ; including supplement use, mean intake was 407 mglday.

    There were no differences in BMD according to diet-only vitamin C intake or combined dietary and supplemental vitamin C intake.

    Longer duration of vitamin C supplement use was associated with higher BMD in women who had not used oestrogen replacement therapy (trend p=0.02) and among women aged 55-64 years (trend p=0.01).

    Women aged 55-64 years who used vitamin C supplements for =10 years had a higher BMD than non-users aged 55-64 years (multi-variate adjusted mean BMD 0.699 (0.017) g/cm2 versus 0.655 (0.007) g/cm2, p=0.02).

    Benefits were not evident in older age groups or in women who had used oestrogen in the past.

    Frequent intake of foods rich in vitamin C was not associated with BMD. (...)

    Mots-clés Pascal : Acide ascorbique, Supplémentation, Régime alimentaire, Masse osseuse, Corrélation, Femme, Homme, Ménopause, Etats Unis, Amérique du Nord, Amérique, Vitamine, Alimentation, Ostéoporose, Système ostéoarticulaire pathologie, Ostéopathie

    Mots-clés Pascal anglais : Ascorbic acid, Supplementation, Diet, Bone mass, Correlation, Woman, Human, Menopause, United States, North America, America, Vitamin, Feeding, Osteoporosis, Diseases of the osteoarticular system, Bone disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0515345

    Code Inist : 002B15A. Création : 13/02/1998.