Study objective-To examine the relationship between dietary vitamin C and hip bone mineral density (BMD) in postmenopausal women.
Design-This was a cross sectional study using retrospective diet and vitamin supplement data.
Setting-The Seattle area of Washington State.
Participants-Screenees for a clinical trial of a drug to prevent osteoporotic fractures ; 1892 women aged 55-80 years who had hip bone densitometry and osteoporosis risk factor information.
Main results-Mean energy adjusted dietary intake of vitamin C was 113 mg/day ; including supplement use, mean intake was 407 mglday.
There were no differences in BMD according to diet-only vitamin C intake or combined dietary and supplemental vitamin C intake.
Longer duration of vitamin C supplement use was associated with higher BMD in women who had not used oestrogen replacement therapy (trend p=0.02) and among women aged 55-64 years (trend p=0.01).
Women aged 55-64 years who used vitamin C supplements for =10 years had a higher BMD than non-users aged 55-64 years (multi-variate adjusted mean BMD 0.699 (0.017) g/cm2 versus 0.655 (0.007) g/cm2, p=0.02).
Benefits were not evident in older age groups or in women who had used oestrogen in the past.
Frequent intake of foods rich in vitamin C was not associated with BMD. (...)
Mots-clés Pascal : Acide ascorbique, Supplémentation, Régime alimentaire, Masse osseuse, Corrélation, Femme, Homme, Ménopause, Etats Unis, Amérique du Nord, Amérique, Vitamine, Alimentation, Ostéoporose, Système ostéoarticulaire pathologie, Ostéopathie
Mots-clés Pascal anglais : Ascorbic acid, Supplementation, Diet, Bone mass, Correlation, Woman, Human, Menopause, United States, North America, America, Vitamin, Feeding, Osteoporosis, Diseases of the osteoarticular system, Bone disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0515345
Code Inist : 002B15A. Création : 13/02/1998.