Nosocomial transmission of multidrug-resistant tuberculosis (MDR TB) has been reported primarily in New York State and has generally been presumed to occur via respiratory aerosols.
- To assess nosocomial transmission of MDR TB.
In 1995,8 patients with MDR TB were identified ih South Carolina ; all were resistant to 7 drugs and had matching DNAfingerprints (strain W1).
Community links were identified for patients (Patients 1-5).
However, no links were identified for the other 3 patients (Patients 6-8) except being hospitalized at the same hospital as 1 community patient.
- Outbreak investigation.
- Community and hospital.
- Eight patients whose MDR TB isolates had DNA fingerprint patterns matching strain W1.
Clinical characteristics of patients with strain W1 Mycobacterium tuberculosis isolates.
- Patient 5 (community patient) and Patient 8, diagnosed April 1995 and November 1995, respectively, had clinical courses consistent with MDR TB, with smear-positive and culture-positive specimens and cavitary lesions on chest radiograph ; both died of MDR TB less than 1 month after diagnosis.
Patients 6 and 7 (diagnosed May 1995) each had 1 positive culture for MDR TB ; specimens were collected during bronchoscopy.
Patient 6 had a skin test conversion after bronchoscopy. (...)
Mots-clés Pascal : Infection nosocomiale, Mycobacterium tuberculosis, Mycobacteriaceae, Mycobacteriales, Actinomycetes, Bactérie, Facteur risque, Bronchoscope, Contamination, Résistance traitement, Enquête sur terrain, Communauté, Hôpital, Evaluation, Homme, Mycobactériose, Bactériose, Infection, Traitement instrumental
Mots-clés Pascal anglais : Nosocomial infection, Mycobacterium tuberculosis, Mycobacteriaceae, Mycobacteriales, Actinomycetes, Bacteria, Risk factor, Bronchoscop, Contamination, Negative therapeutic reaction, Field inquiry, Community, Hospital, Evaluation, Human, Mycobacterial infection, Bacteriosis, Infection, Instrumentation therapy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0515084
Code Inist : 002B05B02O. Création : 13/02/1998.