A population-based case-control study was conducted to elucidate the incidence and etiology of aplastic anemia in Thailand.
Case patients and hospital control patients were enrolled in three regions from 1989 to 1994 ; data were collected by interview.
Forty-six percent of 81 case patients and 19% of 295 control patients from Khonkaen were grain farmers (estimated relative risk [RR]=2.7. 95% confidence interval [CI]=1.4,5.2).
Sixteen percent of case patients and 6% of control patients used agricultural pesticides (estimated RR - 2.7,95% CI : 1.1. 6.6).
The association with grain farming remained among those not exposed to pesticides.
In Songkla, 16% of 43 case patients and 2% of 181 control patients were grain farmers (crude RR estimate - 11. 95% CI - 3.4,35).
The relation of aplastic anemia to grain farming may partly explain the high incidence of aplastic anemia in Thailand.
Mots-clés Pascal : Anémie aplasique, Zone rurale, Santé et environnement, Exposition, Pesticide, Agriculture, Céréale, Epidémiologie, Facteur risque, Incidence, Homme, Thaïlande, Asie, Hémopathie
Mots-clés Pascal anglais : Aplastic anemia, Rural area, Health and environment, Exposure, Pesticides, Agriculture, Cereal, Epidemiology, Risk factor, Incidence, Human, Thailand, Asia, Hemopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0514975
Code Inist : 002B19A01. Création : 13/02/1998.