logo BDSP

Base documentaire

  1. Fulltext. Can dietary interventions change diet and cardiovascular risk factors ? A meta-analysis of randomized controlled trials.

    Article - En anglais



    This study evaluated the effectiveness of dietary advice m primary prevention of chronic disease.


    A meta-analysis was conducted of 17 randomized controlled trials of dietary behavior interventions of at least 3 months'duration.

    Results were analyzed as changes in reported dietary fat intakes and biomedical measures (serum cholesterol, urinary sodium, systolic and diastolic blood pressure) in the intervention group minus changes in the control group at 3 to 6 months and 9 to 18 months of follow-up.


    After 3 to 6 months, mean net changes in each of the five outcomes favored intervention.

    For dietary fat as a percentage of food energy, the change was - 2.5% (95% confidence interval [CI]=-3.9% - 1.1%). Mean net changes over 9 to 18 months were as follows :

    • serum cholesterol,

    • 0.22 (95% CI=-0.39, - 0.05) mmol/L ;

    • urinary sodium.

    • 45.0 (95% CI=-57.1. - 32.8) mmol/24 hours ;

    • systolic blood pressure, 1.9 (95% CI=-3.0,0.8) mm Hg ;

    • and diastolic blood pressure,

    • 1.2 (95% CI=-2.6. 0.2) mm Hg.


    Individual dietary interventions in primary prevention can achieve modest improvements in diet and cardiovascular disease risk status that are maintained for 9 to 18 months.

    Mots-clés Pascal : Appareil circulatoire pathologie, Régime alimentaire, Changement, Facteur risque, Epidémiologie, Evaluation, Efficacité, Homme, Métaanalyse, Etude en condition contrôlée, Randomisation, Alimentation, Prévention

    Mots-clés Pascal anglais : Cardiovascular disease, Diet, Change, Risk factor, Epidemiology, Evaluation, Efficiency, Human, Metaanalysis, Controlled environment study, Randomization, Feeding, Prevention

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0514759

    Code Inist : 002B12B06. Création : 13/02/1998.