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  1. Regional differences in known risk factors and the higher incidence of breast cancer in San Francisco.

    Article - En anglais

    Background 

    The age-adjusted incidence of breast cancer in the San Francisco Bay Area has consistently been higher than that in other regions of the United States.

    The distribution of established risk factors for breast cancer (i.e., parity, age at first full-term pregnancy, breast-feeding, age at menarche, and age at menopause) and probable risk factors (e.g., alcohol consumption) also differs across geographic regions.

    Purpose 

    A study was planned to explore the extent to which differences in the regional distribution of established and probable risk factors could explain the increased incidence of breast cancer in the San Francisco Bay Area.

    Methods 

    Age-adjusted breast cancer incidence rates for January 1978 through December 1982 were obtained for the San Francisco Bay Area and other regions from the Surveillance, Epidemiology, and End Results (SEER) Program.

    Risk factor data from January 1980 through December 1982 were computed from the Cancer and Steroid Hormone Study, a population-based, case-control study of women 22-55 years of age who resided in eight SEER regions.

    Two different statistical methods were used to compute the relative risk (RR) of breast cancer associated with residence in the San Francisco Bay Area versus other regions, after adjusting for regional differences in known risk factors.

    Results 

    Substantial differences in the distribution of breast cancer risk factors were found between the San Francisco Bay Area and other regions. (...)

    Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Incidence, Répartition géographique, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Homme, Glande mammaire pathologie

    Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Incidence, Geographic distribution, Epidemiology, United States, North America, America, Human, Mammary gland diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0513882

    Code Inist : 002B20E02. Création : 13/02/1998.