Physical inactivity and high body mass index (weight in kilograms divided by height in square meters) have been linked to increased risk of colon cancer.
However, none of the few prospective studies in women has shown a statistically significant reduction in colon cancer incidence or mortality associated with increased leisure-time physical activity.
In this prospective study, we asked whether leisure-time physical activity, body mass index, or body fat distribution could significantly influence the risk of colon cancer in women.
The participants in this study were enrolled in the Nurses'Health Study, which began in 1976.
Every 2 years, the women provided additional personal information and information on medical risk factors and major medical events.
The time spent per week at a variety of leisure-time physical activities was determined, and the time spent at each activity was multiplied by its typical energy expenditure, expressed in terms of metabolic equivalents or METs.
The resulting values for each woman were added to yield an MET-hours-per-week score.
Reported diagnoses of colon cancer were confirmed by review of hospital records and pathology reports.
Relative risks and associated 95% confidence intervals were calculated.
In multivariate analyses that included body mass index, women who expended more than 21 MET-hours per week on leisure-time physical activity had a relative risk of colon cancer of 0. (...)
Mots-clés Pascal : Tumeur maligne, Côlon, Facteur risque, Epidémiologie, Exercice physique, Indice masse corporelle, Taille corporelle, Tissu adipeux, Distribution, Femelle, Etats Unis, Amérique du Nord, Amérique, Adulte, Homme, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie
Mots-clés Pascal anglais : Malignant tumor, Colon, Risk factor, Epidemiology, Physical exercise, Body mass index, Body size, Adipose tissue, Distribution, Female, United States, North America, America, Adult, Human, Digestive diseases, Intestinal disease, Colonic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0513880
Code Inist : 002B13B01. Création : 13/02/1998.