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  1. Birth cohort and calendar period trends in breast cancer mortality in the United States and Canada.

    Article - En anglais

    Background 

    Previous studies of regional and temporal variation in U.S. breast cancer mortality rates have been confined largely to analyses of rates for white women.

    Purpose 

    Breast cancer mortality rates from 1969 through 1992 for white women and black women in four regions of the United States and for all women throughout Canada were compared to identify racial, regional, and temporal differences.

    Differences and trends in the rates were evaluated in view of breast cancer risk factors and relevant medical interventions.

    Methods 

    Age-period-cohort models were fit to the data, and changes in birth cohort trends (suggesting a change in a breast cancer risk factor or protective factor) and calendar period trends (suggesting, in part, the impact of new or improved medical interventions) were examined.

    Results 

    Breast cancer mortality rates for white women were significantly higher in the North-east than in any other region of the United States (two-sided t tests ; P<. 005) ; the rates for black women were not.

    Birth cohort trends for all women were similar until about 1940, with a moderation of mortality risk beginning around 1924.

    A marked moderation of risk by 4-year birth cohorts was observed for U.S. white women born after 1950, whereas stable or slightly decreasing trends were observed for U.S. black women and Canadian women.

    For women born from 1924 to around 1938, fertility rates increased for all three groups ; after 1950, they declined uniformly. (...)

    Mots-clés Pascal : Tumeur maligne, Glande mammaire, Mortalité, Epidémiologie, Date naissance, Race, Etats Unis, Amérique du Nord, Amérique, Canada, Homme, Glande mammaire pathologie

    Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Mortality, Epidemiology, Birth date, Race, United States, North America, America, Canada, Human, Mammary gland diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0510550

    Code Inist : 002B20E02. Création : 13/02/1998.