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  1. Effect of the human immunodeficiency virus epidemic on mortality from opportunistic infections in the United States in 1993.

    Article - En anglais

    To measure the effect of the human immunodeficiency virus (HIV) epidemic on mortality from opportunistic infections (OIs) in 1993, national multiple-cause death certificate data were examined using two approaches.

    First, for each OI, the percentage of deaths with HIV infection reported as the underlying cause was calculated.

    Second, the age-adjusted rate of death per million population was compared with the rate predicted from a model of rates in 1970-1980 or 1979-1981, as available.

    The percentage of deaths with HIV as the underlying cause and the ratio of observed to predicted death rates were as follows :

    • toxoplasmosis, 91% and 86 (5.24/0.06) ;

    • cryptosporidiosis/isosporiasis, 90% and infinite (1.61/0.00) ;

    • progressive multifocal leukoencephalopathy, 87% and 19 (2.58/0.13) ;

    • pneumocystosis, 82% and 18 (15.44/0.87) ;

    • cytomegalovirus disease, 82% and 17 (12.60/0.74) ;

    • nontuberculous mycobacteriosis, 79% and 18 (15.51/0.84) ;

    • cryptococcosis, 76% and 4 (5.80/1.35) ;

    • and histoplasmosis, 68% and 6 (1.36/0.23).

    Thus, the HIV epidemic has greatly increased mortality from several OIs.

    Mots-clés Pascal : Infection opportuniste, Homme, Mortalité, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, SIDA, Virose, Infection, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : Opportunistic infection, Human, Mortality, Epidemiology, United States, North America, America, AIDS, Viral disease, Infection, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0502610

    Code Inist : 002B06D01. Création : 13/02/1998.