Review of geographical comparisons of the prevalence of schizophrenic disorders found a ten-fold range difference between geographical contiguous groups, with high and low prevalence pockets.
We performed a 1-year prevalence study of schizophrenia in a limited area of Reunion Island in the Indian Ocean, and analysed the prevalence variability in contiguous regions of this area.
We found one of the highest reported age-corrected (above 15 years) 1-year prevalence of schizophrenia (14.9 per thousand).
Large discrepancies in the distribution of prevalence rates of schizophrenia were observed between the five towns analysed.
Interestingly, when a higher prevalence was observed, it was highly correlated with an increase of the percentage of familial cases (r=0.989, df=3, P=0.0014).
Presence of founder effect often described in geographical isolates could explain the high prevalence rate and the heterogeneity between towns observed in our sample.
Mots-clés Pascal : Prévalence, Schizophrénie, Psychose, Ile Réunion, Iles Océan Indien, Histoire familiale, Epidémiologie, Homme
Mots-clés Pascal anglais : Prevalence, Schizophrenia, Psychosis, Reunion, Indian Ocean Islands, Family story, Epidemiology, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0491092
Code Inist : 002B18C06A. Création : 03/02/1998.