Malignancies, particularly Kaposi's sarcoma and non-Hodgkin's lymphoma (NHL), are associated with human immunodeficiency virus (HIV) infection.
Cancer incidence among 1,073 asymptomatic HIV-infected individuals from the Pulmonary Complications of HIV Infection Study cohort, persons from six states followed from 1988 to 1994, was examined.
Total cancer incidence was 3.99/100 person-years ; for Kaposi's sarcoma, incidence was 2.64 cases/100 person-years, and for NHL, it was 1.18 cases/100 person-years.
Total cancer (n=156 cases) was higher among nonblacks than among blacks (rate ratio=2.8,95% confidence interval 1.3-6.1), with similar results for Kaposi's sarcoma and NHL.
The rate of lung cancer (n=5) among white, homosexual/bisexual males was 0.18 per 100 person-years, suggesting a high risk of lung cancer.
Mots-clés Pascal : SIDA, Virose, Infection, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Tumeur maligne, Complication, Epidémiologie, Incidence, Homme, Etats Unis, Amérique du Nord, Amérique, Etude cohorte, Etude multicentrique, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Malignant tumor, Complication, Epidemiology, Incidence, Human, United States, North America, America, Cohort study, Multicenter study, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0489123
Code Inist : 002B06D01. Création : 03/02/1998.