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  1. Enterotoxin and toxic shock syndrome toxin-1 production of methicillin resistant and methicillin sensitive Staphylococcus aureus strains.

    Article - En anglais

    In this study the production of enterotoxin A-D and toxic shock syndrome toxin-1 (TSST-1) of 181 methicillin resistant (MRSA) and 100 methicillin sensitive (MSSA) Staphylococcus aureus first isolates from different patients was investigated.

    All the MRSA-and MSSA isolates in the study were collected in a period between 1993 and 1995 from specimens sent from 11 different acute care hospitals in the greater Düsseldorf area.

    As far as possible the isolates were matched according to ward and hospital.

    The isolates were collected in the same time period and matched for specimen from which isolated.

    Furthermore, only first isolates were analysed in both groups.

    No significant difference in the production of toxin of any type between MRSA and MSSA could be detected (51 and 40% respectively).

    When the individual toxins were analysed, again no significant difference between MRSA and MSSA was demonstrable (enterotoxin production by MRSA 40% and MSSA 36%, and TSST-I 16% and 8% respectively).

    Despite this, a slight tendency for MRSA to produce enterotoxin A and B and for MSSA to produce enterotoxin C was observed.

    In addition, generation of TSST-I by both groups was independent of enterotoxin A-D production.

    Interestingly, no increase in the proportion of TSST-1-or enterotoxin-producing MRSA and MSSA isolates was observed in strains isolated from blood cultures from patients with a clinical diagnosis of sepsis. (...)

    Mots-clés Pascal : Choc toxique syndrome, Staphylococcie, Bactériose, Infection, Septique syndrome, Staphylococcus aureus, Micrococcaceae, Micrococcales, Bactérie, Chimiothérapie, Méticilline, Antibactérien, Résistance traitement, Sensibilité résistance, Antibiotique, Epidémiologie, Entérotoxine, Production, Lysotype, Homme, Pays Bas, Europe, Pénicilline dérivé, Appareil circulatoire pathologie

    Mots-clés Pascal anglais : Toxic shock syndrome, Staphylococcal infection, Bacteriosis, Infection, Sepsis syndrome, Staphylococcus aureus, Micrococcaceae, Micrococcales, Bacteria, Chemotherapy, Meticillin, Antibacterial agent, Negative therapeutic reaction, Sensitivity resistance, Antibiotic, Epidemiology, Enterotoxin, Production, Lysotype, Human, Netherlands, Europe, Penicillin derivatives, Cardiovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0488987

    Code Inist : 002B05B02N. Création : 03/02/1998.