Time trends in therapeutic approaches and in the prognosis of colon cancer for patients aged 75 years and above have been investigated in comparison with corresponding trends for younger patients using a population-based series of 2089 colon cancer patients diagnosed between 1976 and 1990 in the Cote-d'Or area (478 000 inhabitants), Burgundy, France.
Significant progress has been achieved in the management of patients with colon cancer in both age groups, but trends have been more noticeable in patients aged 75 years and above.
In the elderly, the proportion of cancers limited to the digestive tract wall showed a 3-year average increase of 2.8% (P=0.02) and the frequency of curative surgery an average increase of 8.6% (P<0.001), so that it was performed in 80% of cases in the last 3-year period.
Operative mortality decreased by 2.5% between 3-year periods (P<0.004).
Crude 5-year survival rates in elderly patients increased from 15% in the 1976-78 period to 29% in the 1985-87 period (P<0.001), the corresponding figures being 36% and 44% (P>0.10) in younger patients.
Mots-clés Pascal : Tumeur maligne, Côlon, Stade clinique, Diagnostic, Pronostic, Traitement, Analyse tendance, Variation temporelle, Registre, France, Europe, Vieillard, Homme, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie
Mots-clés Pascal anglais : Malignant tumor, Colon, Clinical stage, Diagnosis, Prognosis, Treatment, Trend analysis, Time variation, Register, France, Europe, Elderly, Human, Digestive diseases, Intestinal disease, Colonic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0487681
Code Inist : 002B13B01. Création : 03/02/1998.