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  1. The Virginia Twin Study of Adolescent behavioral Development influences of age, sex, and impairment on rates of disorder.

    Article - En anglais


    The Virginia Twin Study of Adolescent Behavioral Development is a cohort-longitudinal epidemiological study that uses the genetic twin design to study the development and maintenance of child psychiatric disorders.

    We determined the rates of DSM-III-R disorders, disorders with impairment, and age, sex, and comorbidity effects.


    Families of 2762 white twins aged 8 to 16 years participated.

    Twins and their parents were asked systematically about risk factors and current psychiatric symptoms by means of investigator-based psychiatric interviews and questionnaires.

    The DSM-III-R diagnoses were made for major depressive disorder, separation anxiety, overanxious disorder, simple phobia, social phobia, agoraphobia, oppositional defiant disorder, conduct disorder, and attention deficit hyperactivity disorder.


    The 3-month point prevalence for any DSM-III-R disorders was 413 per 1000, and that for disorders with associated impairment was 142 per 1000.

    Emotional disorders with impairment occurred in 89 per 1000, with girls being more commonly affected ; behavioral disorders had a prevalence of 71 per 1000, with boys being more frequently affected.

    The proportion with disorder who also had functional impairment varied across disorders ; anxiety and phobic disorders were particularly likely not to be accompanied by impairment.

    Rates of emotional and behavioral disorders increased over the age range.

    There was extensive comorbidity among disorders. (...)

    Mots-clés Pascal : Trouble psychiatrique, Adolescent, Homme, Prévalence, Epidémiologie, Virginie, Etats Unis, Amérique du Nord, Amérique, Génétique épidémiologique, Etude familiale, Jumeau, Age, Sexe

    Mots-clés Pascal anglais : Mental disorder, Adolescent, Human, Prevalence, Epidemiology, Virginia, United States, North America, America, Epidemiologic genetics, Family study, Twin, Age, Sex

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0486935

    Code Inist : 002B18C14. Création : 03/02/1998.