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  1. Effect of rapid viral diagnosis on the management of children hospitalized with lower respiratory tract infection.

    Article - En anglais


    Although rapid viral tests are commonly used in children with lower respiratory tract infection, their effect on patient management has not been studied.


    To examine how physicians utilize an enzyme immunoassay for respiratory syncytial virus (RSV EIA) and a centrifugation-enhanced cellular immunofluorescence assay for multiple viral pathogens [viral respiratory panel (VRP) ] in children hospitalized with respiratory illness ; to determine the effect of testing on length of stay, antibiotic use and costs ; and to determine physician attitudes toward RSV testing.

    Design and setting

    Prospective study and survey at a large children's hospital.


    Previously healthy children<24 months of age consecutively admitted between January 1 and February 11,1995, with symptoms of lower respiratory tract infection.


    Of 200 patients 160 were tested by RSV EIA ; 92 were positive and 68 were negative.

    Tested children were younger, more tachypneic and more likely to require oxygen than those not tested.

    Overall the length of stay was similar in RSV-positive and - negative patients.

    Although equal proportions of each group were given antibiotic therapy, RSV-positive children received antibiotic therapy for fewer days than RSV-negative children (median 2 vs. 3 days ; P=0.0387).

    However, a crude cost analysis did not support a strategy of testing all bronchiolitis patients for RSV. (...)

    Mots-clés Pascal : Pneumopathie, Virose, Infection, Bronchiolite, Evaluation performance, Virus respiratoire syncytial humain, Pneumovirus, Paramyxoviridae, Virus, Diagnostic, Enfant, Homme, Immunofluorescence, Méthode immunoenzymatique, Durée, Hospitalisation, Antibiotique, Utilisation, Coût, Appareil respiratoire pathologie, Poumon pathologie, Economie santé, Bronche pathologie

    Mots-clés Pascal anglais : Pneumopathy, Viral disease, Infection, Bronchiolitis, Performance evaluation, Human respiratory syncytial virus, Pneumovirus, Paramyxoviridae, Virus, Diagnosis, Child, Human, Immunofluorescence, Enzyme immunoassay, Duration, Hospitalization, Antibiotic, Use, Costs, Respiratory disease, Lung disease, Health economy, Bronchus disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0485388

    Code Inist : 002B05C02C. Création : 03/02/1998.