Organ transplant recipients and other immunosuppressed patients are known to be at increased risk of nosocomial Legionnaires'disease.
Although the ecology of Legionella in hospital water storage and distribution systems (including a protozoonotic relationship with free-living protozoa) has been well documented, little is known regarding the quality of water supplied to high-risk units.
Hot-and cold-water samples (two first draw and one run to waste for 5 min) were taken from 69 (85%) of the 81 United Kingdom organ transplant units (31 renal, 24 bone marrow, nine cardiopulmonary and five liver transplant units) and cultured for Legionella and protozoa.
Legionella spp. were isolated from the water supplies of 38 (55%) units and Legionella pneumophila from 31 (45%). The blue-white fluorescent group of Legionella (Legionella gormanii, Legionella bozemanii and others) was isolated from 18 (26%) units.
Free-living protozoa were isolated from 47 units (68%) and genera of the protozoa known to permit the intracellular growth of Legionella (PGIGL), from 40 units (58%). Possible associations between Legionella and the variables Protozoa ; PGIGL ; water pH ; and circulating water temperature (recorded after running to waste for 5 min) were examined by logistic regression analysis.
In cold-water supplies, a significant association was found between the isolation of Legionella and PGIGL (P=0032 ; OR=1.81 ; 95% CI 1.1-3.1). (...)
Mots-clés Pascal : Protozoa, Legionella, Legionellaceae, Bactérie, Colonisation, Approvisionnement eau, Service hospitalier, Hôpital, Chirurgie, Transplantation, Prévention, Infection nosocomiale, Qualité eau, Méthode, Surveillance sanitaire, Hygiène
Mots-clés Pascal anglais : Protozoa, Legionella, Legionellaceae, Bacteria, Colonization, Water supply, Hospital ward, Hospital, Surgery, Transplantation, Prevention, Nosocomial infection, Water quality, Method, Sanitary surveillance, Hygiene
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0482641
Code Inist : 002B05B02E. Création : 03/02/1998.