The authors conducted a case-control study among the multi-ethnic population of Hawaii to examine the role of dietary soy, fiber, and related foods and nutrients on the risk of endometrial cancer.
Endometrial cancer cases (n=332) diagnosed between 1985 and 1993 were identified from the five main ethnic groups in the state (Japanese, Caucasian, Native Hawaiian, Filipino, and Chinese) through the rapid-reporting system of the Hawaii Tumor Registry.
Population controls (n=511) were selected randomly from lists of female Oahu residents and matched to cases on age (±2.5 years) and ethnicity.
All subjects were interviewed using a diet history questionnaire that included over 250 food items.
Non-dietary risk factors for endometrial cancer included nulliparity, never using oral contraceptives, fertility drug use, use of unopposed estrogens, a history of diabetes mellitus or hypertension, and a high Quetelet's index (kg/m2).
Energy intake from fat, but not from other sources, was positively associated with the risk of endometrial cancer.
The authors also found a positive, monotonic relation of fat intake with the odds ratios for endometrial cancer after adjustment for energy intake.
The consumption of fiber, but not starch, was inversely related to risk after adjustment for energy intake and other confounders.
Similar inverse gradients in the odds ratios were obtained for crude fiber, non-starch polysaccharide, and dietary fiber. (...)
Mots-clés Pascal : Tumeur maligne, Endomètre, Produit à base de soja, Fibre alimentaire, Graisse, Régime alimentaire, Epidémiologie, Facteur risque, Femme, Homme, Hawaï, Polynésie, Océanie, Ethnie, Etude comparative, Appareil génital femelle pathologie, Utérus pathologie, Alimentation
Mots-clés Pascal anglais : Malignant tumor, Endometrium, Soy product, Dietary fiber, Grease, Diet, Epidemiology, Risk factor, Woman, Human, Hawaii, Polynesia, Oceania, Ethnic group, Comparative study, Female genital diseases, Uterine diseases, Feeding
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0478955
Code Inist : 002B20C02. Création : 03/02/1998.