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  1. Fulltext. National trends in the mortality of children with sickle cell disease, 1968 through 1992.

    Article - En anglais



    This paper describes national trends in mortality of children with sickle cell disease and the settings in which death occurred.


    United States death certificate data from 1968 through 1992 were used to calculate mortality rates of Black children with sickle cell disease 1 to 14 years old.

    Deaths from trauma, congenital anomalies, and perinatal conditions were excluded.


    Between 1968 and 1992, mortality rates of Black children with sickle cell disease decreased 41% for 1-to 4-year-olds 47% for 5-to 9-year-olds, and 53% for 10-to 14-year-olds.

    During 1986 through 1992, children who died before hospital admission accounted for 41% of deaths among 1-to 4-year-oids, 27% among 5-to 9-year-olds, and 12% among 10-to 14-year-olds.


    Survival of Black children with sickle cell disease has improved markedly since 1968.

    A substantial proportion of deaths continue to occur prior to hospital admission.

    Trends in sickle cell mortality can be monitored inexpensively with death-certificate data.

    Mots-clés Pascal : Anémie hématie falciforme, Taux, Epidémiologie, Mortalité, Evolution, Tendance, Enfant, Homme, Etats Unis, Amérique du Nord, Amérique, Hémopathie, Anémie hémolytique, Hémoglobinopathie, Maladie héréditaire

    Mots-clés Pascal anglais : Sickle cell anemia, Rate, Epidemiology, Mortality, Evolution, Trend, Child, Human, United States, North America, America, Hemopathy, Hemolytic anemia, Hemoglobinopathy, Genetic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0478720

    Code Inist : 002B19A01. Création : 03/02/1998.