Are omphalocele and neural tube defects related congenital anomalies ? Data from 21 registries in Europe (EUROCAT).
We have analyzed the association between omphalocele and neural tube defects (O/NTD) previously reported in epidemiological studies of EUROCAT registry data [Dolk et al., 1991 ; Calzolari et al., 1995]. By examining differences in prevalence between the United Kingdom and Ireland (UKI) and Continental Europe and Malta (CEM) and differences in sex ratio, the possible etiopathogenetic differences between O/NTD association and omphalocele without NTD and NTD without omphalocele were investigated.
The distribution of O/NTD cases according to NTD site in the two geographic areas shows in the UKI a tendency for omphalocele to associate with anencephaly/spina bifida and with anencephaly.
In CEM centers, these types of NTD are much rarer.
The pattern of other anomalies occurring in combination with O/NTD association in the same babies was also analysed.
Mots-clés Pascal : Malformation, Tube neural, Homme, Omphalocèle, Association, Epidémiologie, Etiopathogénie, Royaume Uni, Europe, Irlande, Malte, Paroi abdominale, Système nerveux pathologie, Système nerveux central pathologie, Maladie congénitale, Abdomen pathologie
Mots-clés Pascal anglais : Malformation, Neural tube, Human, Omphalocele, Association, Epidemiology, Etiopathogenesis, United Kingdom, Europe, Ireland, Malta, Abdominal wall, Nervous system diseases, Central nervous system disease, Congenital disease, Abdominal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0472369
Code Inist : 002B17D. Création : 03/02/1998.