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  1. Are omphalocele and neural tube defects related congenital anomalies ? Data from 21 registries in Europe (EUROCAT).

    Article - En anglais

    We have analyzed the association between omphalocele and neural tube defects (O/NTD) previously reported in epidemiological studies of EUROCAT registry data [Dolk et al., 1991 ; Calzolari et al., 1995]. By examining differences in prevalence between the United Kingdom and Ireland (UKI) and Continental Europe and Malta (CEM) and differences in sex ratio, the possible etiopathogenetic differences between O/NTD association and omphalocele without NTD and NTD without omphalocele were investigated.

    The distribution of O/NTD cases according to NTD site in the two geographic areas shows in the UKI a tendency for omphalocele to associate with anencephaly/spina bifida and with anencephaly.

    In CEM centers, these types of NTD are much rarer.

    The pattern of other anomalies occurring in combination with O/NTD association in the same babies was also analysed.

    Mots-clés Pascal : Malformation, Tube neural, Homme, Omphalocèle, Association, Epidémiologie, Etiopathogénie, Royaume Uni, Europe, Irlande, Malte, Paroi abdominale, Système nerveux pathologie, Système nerveux central pathologie, Maladie congénitale, Abdomen pathologie

    Mots-clés Pascal anglais : Malformation, Neural tube, Human, Omphalocele, Association, Epidemiology, Etiopathogenesis, United Kingdom, Europe, Ireland, Malta, Abdominal wall, Nervous system diseases, Central nervous system disease, Congenital disease, Abdominal disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0472369

    Code Inist : 002B17D. Création : 03/02/1998.