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  1. Pretransplant renal dysfunction predicts poorer outcome in liver transplantation.

    Article - En anglais

    The postoperative courses of 115 liver transplant recipients were reviewed to monitor for outcomes of acute renal failure and mortality.

    An analysis of baseline (preoperative) variables with particular attention to baseline renal function was accomplished to establish predictive variables for a complicated postoperative course.

    Acute renal failure requiring dialysis occurred in 27 cases (23%) and was associated with a prolonged ICU stay, greater infectious complications, greater hospital charges and a high mortality rate (46 ± 11% vs. 9 ± 3%) as compared to patients who did not experience acute renal failure.

    Death occurred in 20 patients (17%) overall prior to discharge.

    In order to assess the contribution of renal function, the population was divided arbitrarily into two groups based on preoperative serum creatinine.

    Group I (n=50) had a preoperative serum creatinine<1.0 mg/dl (mean ± SD=2.2 ± 0.2 mg/dl) and Group 2 (n=65) had a preoperative serum creatinine ¾1.0 mg/dl (0.7 ± 0.1 mg/dl).

    The groups experienced similar operative courses.

    Group 1 patients experienced significantly longer ICU stays (18 ± 3 vs. 10 ± 2 days), higher rates of acute renal failure requiring dialysis (52 ± 7 vs. 5 ± 2%), higher hospital charges (231,454 ± 17,088 vs. 178,755 ± 14,744 $, US) and a greatly increased mortality rate (32 ± 1 vs. 6 ± 1%), as compared to Group 2 patients. (...)

    Mots-clés Pascal : Transplantation, Foie, Valeur prédictive, Evolution, Réussite, Insuffisance rénale, Mortalité, Coût, Etude statistique, Homme, Chirurgie, Appareil digestif pathologie, Foie pathologie, Appareil urinaire pathologie, Rein pathologie, Economie santé

    Mots-clés Pascal anglais : Transplantation, Liver, Predictive value, Evolution, Achievement, Renal failure, Mortality, Costs, Statistical study, Human, Surgery, Digestive diseases, Hepatic disease, Urinary system disease, Kidney disease, Health economy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0472053

    Code Inist : 002B25G03. Création : 03/02/1998.