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  1. Obsessive-compulsive disorder in pregnancy, the puerperium, and the premenstruum.

    Article - En anglais


    Recent reports suggest that pregnancy and the puerperium may precipitate or exacerbate obsessive-compulsive disorder (OCD).

    The influence of this illness on other reproductive events, such as the premenstruum, is unknown.

    We examined retrospectively the relationships of pregnancy, the puerperium, and premenstruum to the course of OCD in 57 women.


    Women outpatients with OCD meeting DSM-III-R criteria completed a standardized telephone interview administered by a psychiatric resident.

    They were asked retrospectively about the clinical course of their illness premenstrually and during and after pregnancy.


    Of 72 women eligible for the study, 79% (N=57) completed the interview.

    Premenstrual worsening of OCD was described by 24 (42%) of the 57 women, and 12 (21%) described premenstrual dysphoria.

    Of the 57 women, 38 (67%) had been pregnant at least once ; 31 (54%) had delivered at least one child.

    Pregnancy was associated with the onset of OCD in only 5 (13%) of the 38 women.

    Of the 29 women with preexisting OCD who became pregnant, 20 (69%) described no change in symptoms during pregnancy, 5 (17%) described worsening, and 4 (14%) described improvement.

    Postpartum exacerbation of OCD symptoms was reported by 7 (29%) of the 24 women with preexisting OCD who completed full-term pregnancies.

    Nine (37%) of the 24 women with both preexisting OCD and completed pregnancies also reported postpartum depression. (...)

    Mots-clés Pascal : Obsession compulsion, Trouble anxieux, Gestation, Postpartum, Etude longitudinale, Epidémiologie, Facteur risque, Adulte, Homme, Femelle, Prémenstruel

    Mots-clés Pascal anglais : Obsessive compulsive disorder, Anxiety disorder, Pregnancy, Puerperium, Follow up study, Epidemiology, Risk factor, Adult, Human, Female, Premenstrual

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0469019

    Code Inist : 002B18C08B. Création : 03/02/1998.