As part of a longitudinal study two urine samples (survey 1 in 1991 and survey 2 in 1992) were collected from 602 elementary school children to investigate the relationship between urinary cotinine excretion (UCE) and the daily consumption of cigarettes at home (exposure).
Size of the dwelling, educational level, and maternal smoking were taken into consideration as additional predictors.
The history regarding parental smoking habits and confounding variables was ascertained by standardized questionnaires completed by the parents.
Cotinine was measured using gas chromatography selected ion monitoring.
UCE was expressed as cotinine/creatinine (ng/mg).
In children with detectable UCE in survey 1 (35%) and in survey 2 (44%) the excretion ranged between 1.5 and 24.7 ng/mg (5-95%) and between 1.2 and 25.2 ng/mg, respectively.
UCE measurements in both surveys were highly correlated (r=0.65, P=0.0001), and 59.6% of the UCE in survey 2 can be explained in linear regression by the UCE in survey 1. Using multiple linear regression, the categorized number of cigarettes reported to be consumed at home (20 cigarettes and more : 1991, P=0.0001 ; 1992, P=0.0003) and low educational level of the parents (P=0.011 in 1991, P=0.04 in 1992) were positively associated with UCE, whereas the size of the dwelling turned out to be negatively associated with UCE (P=0.12 in 1991, P=0.001 in 1992).
In small dwellings (¾80 m2) the effect of exposure on UCE was much more pronounced. (...)
Mots-clés Pascal : Tabagisme passif, Pollution intérieur, Enfant, Homme, Age scolaire, Epidémiologie, Milieu familial, Logement habitation, Statut socioéconomique, A domicile, Etude longitudinale
Mots-clés Pascal anglais : Passive smoking, Indoor pollution, Child, Human, School age, Epidemiology, Family environment, Housing, Socioeconomic status, At home, Follow up study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0466529
Code Inist : 002B03E. Création : 03/02/1998.