In a case-control study of 217 hospitalized incident cases of ischemic heart disease and 261 controls we compared various anthropometric indices for the strength of their associations to the outcome event.
The ratio of supine sagittal abdominal diameter to midthigh girth ( « abdominal diameter index » ; ADI) was the simple index that best discriminated cases from controls for both men (standardized difference, 0.65 ; p<0.0001) and women (standardized difference, 0.95 ; p<0.0001).
The waist-to-thigh ratio of girths (WTR) (standardized difference, 0.57 and 0.90 ; p<0.0001) was nearly as strong as the ADI and stronger than the traditional waist-to-hip ratio (standardized difference, 0.34 and 0.68 ; p<0.005).
After adjustments for age and race, the men's odds ratio for ischemic heart disease (tertile 3 vs. tertile 1) was 5.5 (95% CI, 2.9-10) using ADI and 5.1 (2.6-10) using the WTR.
The women's odds ratio was 6.3 (1.9-20) using ADI and 8.7 (2.3-33) using the WTR.
Further adjustments for body mass index and cardiovascular risk factors did not substantially change these risk estimates.
Similar odds ratios were estimated by analyses restricted to 169 neighborhood-matched case-control pairs.
In contrast, increased midthigh girth and subcutaneous fat mass (sum of three skinfolds) were associated with a protective effect against ischemic heart disease. (...)
Mots-clés Pascal : Infarctus, Myocarde, Anthropométrie, Poids corporel, Obésité, Abdomen, Epidémiologie, Facteur risque, Homme, Etats Unis, Amérique du Nord, Amérique, Etude cas témoin, Appareil circulatoire pathologie, Cardiopathie coronaire, Myocarde pathologie, Biométrie corporelle
Mots-clés Pascal anglais : Infarct, Myocardium, Anthropometry, Body weight, Obesity, Abdomen, Epidemiology, Risk factor, Human, United States, North America, America, Case control study, Cardiovascular disease, Coronary heart disease, Myocardial disease, Corporal biometry
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0466036
Code Inist : 002B12A03. Création : 03/02/1998.