logo BDSP

Base documentaire


Votre avis nous intéresse

Le réseau BDSP met en oeuvre un projet d'innovation et d'amélioration de ses services, dans le souci constant de proposer des contenus de qualité adaptés aux besoins des utilisateurs.

Identifier de nouvelles sources de financements est la condition nécessaire pour assurer la poursuite et la pérennité de cet outil unique qu'est la BDSP, tout en le faisant évoluer.

Pour définir un nouveau modèle économique, nous avons besoin de votre avis : merci de répondre à notre enquête (temps estimé : 5 minutes).

Participer maintenant
Participer plus tard J'ai déjà participé

  1. Malignant hypertension in young women is related to previous hypertension in pregnancy, not oral contraception.

    Article - En anglais

    Previous studies have suggested that one-third of women of childbearing age who develop malignant phase hypertension (MHT) are likely to be taking oral contraceptives (OC).

    We surveyed 104 women with a history of MHT.

    None of the 65 aged>45 years were taking OC or other sex hormones.

    Thirty-nine (mean age 34.9 years, SD 8.0) were aged 15-44 years at presentation : 22 Caucasian, 10 Black/Afro-Caribbean and seven Indo-Asian.

    Of these 39,22 had a history of hypertension in pregnancy (group 1), and 17 did not (group 2).

    Three of group 1 also had a history of OC-induced hypertension.

    None were pregnant, but one was taking an OC at presentation with MHT.

    Blood pressures at presentation and follow-up, and mean serum urea and creatinine at presentation were similar between groups, as was median survival (96 vs. 47 months, Lee-Desu statistic 0.75, p=0.38).

    There was a trend towards poorer renal function at follow-up in group 1 patients, with higher mean serum urea and creatinine levels.

    The causes of death were renal failure (5), stroke (4) and heart disease (2).

    The OC was not a common cause of MHT amongst our sample of women of childbearing age, but a past history of hypertension in pregnancy was important.

    Such patients also had a longer duration of hypertension and poorer renal function at follow-up.

    Mots-clés Pascal : Hypertension artérielle maligne, Association, Gestation, Enquête publique, Voie orale, Contraceptif, Etude comparative, Evaluation, Homme, Femelle, Appareil circulatoire pathologie, Vaisseau sanguin pathologie

    Mots-clés Pascal anglais : Malignant hypertension, Association, Pregnancy, Public inquiry, Oral administration, Contraceptive, Comparative study, Evaluation, Human, Female, Cardiovascular disease, Vascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0461369

    Code Inist : 002B20F02. Création : 03/02/1998.