Although ammonium acid urate (AAU) stones are endemic in Asia, pure AAU calculi have almost disappeared from industrialized countries and clinical pathophysiologic relevance of sporadic stones containing AAU crystals is currently unknown.
We reviewed 1,396 crystallographic stone analyses performed in our institution over a 10-year period.
Prevalence of stones containing AAU crystals and predominantly AAU stones were 3.1% and 0.2%, respectively.
In more than two thirds of cases, AAU crystals represented less than 10% of stone crystal composition.
No pure AAU stone was found.
According to crystalline predominance, 42%, 35%, and 12% of these calculi were uric acid, infectious, and calcium oxalate stones, respectively.
AAU crystals were detected as discrete intercrystalline or peripheral deposits in 74.4% of stones.
In only one calculus was AAU crystals detected in the nucleus.
The hospital charts of 37 patients who presented with 43 calculi containing AAU crystals were also reviewed.
The mean age was 53.1 ± 16.6 years.
Fifty-seven percent of calculi were upper urinary tract stones and 43% were bladder stones.
Upper urinary tract calculi were more frequently uric acid stones, followed by infectious and calcium oxalate stones.
Lower urinary tract calculi were more frequently infectious stones, followed by uric acid stones.
Upper urinary tract stones were passed spontaneously in 13 patients and removed surgically in nine patients. (...)
Mots-clés Pascal : Lithiase, Voie urinaire, Incidence, Composition chimique, Ammonium composé, Urique acide, Localisation, Facteur risque, Epidémiologie, Homme, Appareil urinaire pathologie, Voie urinaire pathologie, Uretère pathologie, Calcul urinaire
Mots-clés Pascal anglais : Lithiasis, Urinary tract, Incidence, Chemical composition, Ammonium compound, Uric acid, Localization, Risk factor, Epidemiology, Human, Urinary system disease, Urinary tract disease, Ureteral disease, Urinary stone
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0461346
Code Inist : 002B14B. Création : 03/02/1998.