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  1. Gallstone prevalence in relation to smoking, alcohol, coffee consumption, and nutrition : The Ulm Gallstone Study.

    Article - En anglais

    Background 

    Besides considering well-known risk factors for the development of gallbladder stones, such as age, sex, fecundity, and hereditary predisposition, efforts at prevention have focused increasingly on other factors, such as nicotine, alcohol, and caffeine consumption, as well as general nutrition, which may be modified.

    Methods 

    A total of 1116 blood donors were examined between April 1994 and February 1995 in the central blood bank of the German Red Cross in Ulm, Germany.

    Each subject received a questionnaire and underwent to an upper abdominal ultrasound examination.

    Results 

    Gallbladder stone disease (current cholecystolithiasis and history of cholecystectomy) was detected in 5.8% of the men and 6.3% of the women.

    Neither regularity nor number of daily meals correlated with the frequency of gallstone disease.

    Vegetarians (n=48), as a group, were not found to have gallstones.

    In relation to the consumption of alcohol, tobacco, or caffeine, a slightly higher prevalence of cholecystolithiasis was found only in heavy drinkers of coffee (P=0.051 ; odds ratio (OR), 1.083 ; 95% confidence interval (CI), 0.999,1.174).

    Conclusion 

    Results of the present study do not show a definite relationship between nutritional factors and the consumption of alcohol, tobacco, or caffeine and an increased prevalence of gallbladder stone disease.

    Mots-clés Pascal : Lithiase, Voie biliaire, Prévalence, Tabagisme, Alcoolisme, Café, Consommation, Nutrition, Facteur risque, Imagerie ultrasonore, Epidémiologie, Homme, Allemand, Voie biliaire pathologie, Appareil digestif pathologie, Toxicologie, Prévention, Métabolisme pathologie, Radiodiagnostic, Imagerie médicale

    Mots-clés Pascal anglais : Lithiasis, Biliary tract, Prevalence, Tobacco smoking, Alcoholism, Coffee, Consumption, Nutrition, Risk factor, Ultrasound imaging, Epidemiology, Human, German, Biliary tract disease, Digestive diseases, Toxicology, Prevention, Metabolic diseases, Radiodiagnosis, Medical imagery

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0461206

    Code Inist : 002B13C03. Création : 03/02/1998.