In a population-based case-control study of colon carcinoma and nutrition involving the francophone community in Greater Montreal, a total of 402 cases (200 males and 202 females) and 668 controls (239 males and 429 females) were interviewed.
Cases from 1989-1993 were identified through the admission offices of 5 major francophone teaching hospitals in Montreal and were ages 35-79 years.
Controls matched by age, place of residence, and language were selected by a modified random digit dialing method.
Information on dietary intake was collected with a quantitative food frequency questionnaire.
No associations were evident between colon carcinoma and total energy, protein, or carbohydrate consumption, whereas a suggestive inverse association was found with total fat intake, with an odds ratio (OR) of 0.78 (P=0.0637), and with saturated fat intake as well (OR=0.71, P=0.0893).
A strongly significant inverse association was found with dietary fiber (OR=0.50, P=0.0018).
The strongest inverse association concerning fiber was found with fiber from vegetable sources (OR=0.57, P=0.0096), and a suggestive (although nonsignificant) inverse association (OR=0.74, P=0.0687) was found with fiber from fruits.
Calcium was inversely associated with risk (OR=0.69, P=0.0411), as was dietary intake of vitamin A (OR=0.67, P=0.0162), retinol, (OR=0.069, P=0.0409), vitamin E (OR=0.53, P=0.0028), and alphatocopherol (OR=0.63, P=0.0256). (...)
Mots-clés Pascal : Carcinome, Côlon, Facteur risque, Epidémiologie, Nutrition, Fibre alimentaire, Matière grasse, Vitamine, Français, Québec, Canada, Amérique du Nord, Amérique, Etude cas témoin, Homme, Tumeur maligne, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Montréal
Mots-clés Pascal anglais : Carcinoma, Colon, Risk factor, Epidemiology, Nutrition, Dietary fiber, Fat, Vitamin, French, Quebec, Canada, North America, America, Case control study, Human, Malignant tumor, Digestive diseases, Intestinal disease, Colonic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0455753
Code Inist : 002B13B01. Création : 03/02/1998.