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  1. Fulltext. The variability of exposure over time : A prospective longitudinal study.

    Article - En anglais


    Four hundred and forty personal air measurements were carried out on 54 workers, employed in the main processes in six different factories (6-13 in each).

    Potential exposure was to lead, benzene and dust.

    Ten randomly repeated hygiene surveys were carried out over 1 year.

    In order to estimate the magnitude of the variability in workers'exposure over time, its sources, the variance between workers and the variance within a worker, a nested unbalanced analysis-of-variance model was fitted to the log-transformed data.

    Of the total exposure variance, the within variance of a worker's exposure over time was 51% (geometrical standard deviation, GSD=3.1) and the between workers, factories and air contaminants variance was 49%. The exposure variance between all the workers was due mainly to variance between workers within the same factory (67%). Outdoor locations, mobility of the worker and mobility of the sources of exposure result in a positive influence on both the variance between (26%, ANOVA) and the variance of a worker over time (39%, regression).

    These variables are therefore important in the sampling strategy of workers'exposure.

    For valid compliance testing and assessment of workers'exposure the mean and the within-and between-variance of the workers'exposure over time should be considered.

    The exposure should be measured several times a year randomly in order to prevent workers misclassification.

    To assess yearly exposure, a GSD=3. (...)

    Mots-clés Pascal : Composé chimique, Industrie, Exposition professionnelle, Médecine travail, Homme, Variabilité, Etude temporelle, Temps exposition, Etude longitudinale, Hygiène travail, Israël, Asie, Etude cohorte, Analyse variance, Analyse statistique

    Mots-clés Pascal anglais : Chemical compound, Industry, Occupational exposure, Occupational medicine, Human, Variability, Temporal study, Exposure time, Follow up study, Occupational hygiene, Israel, Asia, Cohort study, Variance analysis, Statistical analysis

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0455119

    Code Inist : 002B03L01. Création : 03/02/1998.