A thermal desorption-gas chromatography (GC) system was developed for use with commercial adhesive plasters used for monitoring exposure of hands to common solvents.
The efficiency of solvent adsorption on the activated carbon pads located on the plasters was determined for acetone, trichloroethylene, D-limonene, methanol, ethyl methyl ketone, toluene, tetrachloroethylene and m-xylene.
The degree of solvent recovery for the system was also investigated for each solvent, as was its sensitivity and reproducibility.
All solvents exhibited>90% adsorption on the pads at spiking levels of 100-200 ng for each solvent, except for m-xylene and d-limonene.
Solvent recovery was dependent on the volatility of the solvent at spiking volumes of about 1 mul per pad with solvents with boiling points above 110 °C showing recoveries of<75%. Increasing primary desorption times and temperatures increased these values.
The precision was good with RSD<5% for all solvents over the range 0.5-5.0 mul of applied solvent.
It was possible to detect 15-60 ng of each solvent component within solvent mixtures on the pads with the exception of D-limonene.
It is concluded that all solvents tested except D-limonene can be determined on the pads under the conditions for thermal desorption-GC analysis described.
The pads were used under protective gloves with six workers using xylene isomers as solvent in the workplace, when apparent solvent breakthrough through their gloves was observed.
Mots-clés Pascal : Exposition professionnelle, Lieu travail, Solvant organique, Dose limite, Test cutané, Coussinet adhésif, Méthode analyse, Chromatographie phase gazeuse, Thermodésorption
Mots-clés Pascal anglais : Occupational exposure, Work place, Organic solvent, Limit dose, Skin test, Adhesive pad, Analysis method, Gas chromatography, Thermodesorption
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0452804
Code Inist : 001D16C06. Création : 03/02/1998.