Although gastric cancer and duodenal ulcer are both related to Helicobacter pylori infection, they are mutually exclusive diseases such that patients with a history of duodenal ulcer have a markedly reduced risk of developing gastric cancer.
It has been hypothesized that different strains of H. pylori may be related to the different diseases.
Our aim was to study the prevalence of duodenal ulcer disease and gastric cancer in dyspeptic patients in South Korea, a country with a high incidence of gastric cancer.
The study population consisted of consecutive patients between the ages of 20 and 81 years referred to Guro Hospital's Endoscopic Unit for evaluation of dyspepsia.
Patients with a history of peptic ulcer or gastric cancer were excluded.
Each patient underwent endoscopy and completed a detailed questionnaire.
Peptic ulcer was defined as the presence of an active ulcer, red scar, or white scar.
One thousand patients were evaluated, and 867 (43% men and 57% women) met the entry criteria.
The prevalence of peptic ulcer and gastric cancer were 24% and 7%, respectively.
Among peptic ulcer patients, duodenal ulcer was commoner (75%) than gastric ulcer or coexistent duodenal and gastric ulcer (21% and 4%, respectively).
The mean age of duodenal and gastric ulcer patients (45+14 and 48 ± 12 years, respectively) was significantly lower than that of gastric cancer patients (59 ± 11 years) (P<0.01). (...)
Mots-clés Pascal : Dyspepsie, Incidence, Complication, Ulcère, Duodénum, Carcinome, Estomac, Epidémiologie, Homme, Appareil digestif pathologie, Intestin pathologie, Tumeur maligne, Estomac pathologie
Mots-clés Pascal anglais : Dyspepsia, Incidence, Complication, Ulcer, Duodenum, Carcinoma, Stomach, Epidemiology, Human, Digestive diseases, Intestinal disease, Malignant tumor, Gastric disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0450171
Code Inist : 002B13B01. Création : 03/02/1998.