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  1. Fulltext. Comparison of self-reported and database-linked family history of cancer data in a case-control Study.

    Article - En anglais


    The authors linked interview data drawn from Utah participants in the Diet, Activity, and Reproduction in Colon Cancer (DARCC) Study (1992-1995) to genealogic and cancer information contained in the Utah Population Database (UPDB).

    They evaluated the sensitivity of subjects'reports of familial cancers and measured the overall agreement between reported and database records with the kappa (K) statistic.

    They calculated odds ratios from logistic regression to compare the relative risk estimates that would result from use of either data set (or both data sets).

    Overall, 37.6% (331 of 881) of the Utah DARCC subjects were linked to the UPDB genealogy.

    High sensitivities were observed for subjects'reports of breast (83%), colorectal (73%), and prostate (70%) cancers, while ovarian (60%) and uterine (30%) cancers were not reported as well.

    Results for K were similar, with values of 0.63 for breast cancer and 0.56 for colorectal cancer.

    Although the observed Ks of 0.36 and 0.25 for ovarian and uterine cancers, respectively, exceeded chance expectations, the agreement between subjects'reports and database records was unimpressive.

    No consistent difference was observed between cases and controls in the accuracy of self-reports.

    In general, higher sensitivities were observed among younger subjects than older subjects ; females reported family histories of cancer only slightly better than males. (...)

    Mots-clés Pascal : Tumeur maligne, Côlon, Histoire familiale, Antécédent, Base donnée, Donnée, Autoévaluation, Epidémiologie, Risque, Homme, Etats Unis, Amérique du Nord, Amérique, Etude comparative, Etude cas témoin, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie

    Mots-clés Pascal anglais : Malignant tumor, Colon, Family story, Antecedent, Database, Data, Self evaluation, Epidemiology, Risk, Human, United States, North America, America, Comparative study, Case control study, Digestive diseases, Intestinal disease, Colonic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0447449

    Code Inist : 002B04B. Création : 03/02/1998.