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  1. Spine update tuberculosis of the spine : Controversies and a new challenge.

    Article - En anglais

    Tuberculosis is a deadly disease affecting many people in the world.

    The prevalence of spinal tuberculosis is likely to rise as the numbers of those infected with human immunodeficiency virus rises.

    This presentation summarizes present knowledge of spinal tuberculosis and its management.

    It describes and updates material the author has previously published on this subject.

    The scientific basis for the clinical management of spinal tuberculosis has been well established by the British Medical Research Council group and Hong Kong surgeons.

    It is believed, however, that well-controlled basic and clinical studies are required if the incidence of the three unwanted complications of spinal tuberculosis is to be reduced further.

    Antituberculosis agents are the mainstay of management, with chemotherapy for 12 months preferred to shorter courses.

    The standard is a combination of isoniazid, rifampin, and pyrazinamide, with or without ethambutol.

    Anterior surgery consisting of radical focal debridement without fusion does not prevent vertebral collapse.

    The major advantage of anterior arthrodesis is the decreased tendency for progression of the deformity.

    Patients who present late with deformity are candidates for anterior débridement and stabilization with corrective instrumentation.

    Posterior stabilization with instrumentation has been found to help arrest the disease and to bring about early fusion. (...)

    Mots-clés Pascal : Spondylodiscite, Tuberculose, Mycobactériose, Bactériose, Infection, Epidémiologie, Incidence, Symptomatologie, Complication, Traitement, Article synthèse, Homme, Rachis, Système ostéoarticulaire pathologie, Rachis pathologie

    Mots-clés Pascal anglais : Spondylitis, Tuberculosis, Mycobacterial infection, Bacteriosis, Infection, Epidemiology, Incidence, Symptomatology, Complication, Treatment, Review, Human, Spine, Diseases of the osteoarticular system, Spine disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0443994

    Code Inist : 002B05B02J. Création : 03/02/1998.