Prognostic factors in meningococcal disease : Development of a bedside predictive model and scoring system.
Context. - Meningococcal disease is associated with significant morbidity and mortality.
Development of a prognostic model based on clinical findings may be useful for identification and management of patients with meningococcal infection.
- To construct and validate a bedside model and scoring system for prognosis in meningococcal disease.
- Prospective, population-based study.
- Twenty-four hospitals in the metropolitan area of Barcelona, Spain.
- A total of 907 patients with microbiologically proven meningococcal disease.
Patients diagnosed with meningococcal disease from 1987 through 1990 were used to develop the prognostic model, and those diagnosed in 1991 and 1992 were used to validate it.
- Clinical independent prognostic factors for mortality in meningococcal disease.
The association between outcome and independent prognostic factors was determined by logistic regression analysis.
A scoring system was constructed and tested using receiver operating characteristic curves.
- Among 624 patients in the derivation set, 287 (46%) were male, the mean age was 12.4 years, and 34 patients (5.4%) died.
Among 283 patients in the validation set, 124 (43.8%) were male, the mean age was 12.7 years, and 17 patients (6.0%) died. (...)
Mots-clés Pascal : Méningococcie, Bactériose, Infection, Méthodologie, Pronostic, Echelle évaluation, Evaluation performance, Homme, Espagne, Europe
Mots-clés Pascal anglais : Meningococcal disease, Bacteriosis, Infection, Methodology, Prognosis, Evaluation scale, Performance evaluation, Human, Spain, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0432981
Code Inist : 002B30A01A1. Création : 19/12/1997.