Black/white differences in leukocyte subpopulations in men.
Although counts of leukocytes differ substantially between blacks and whites, and are predictive of ischaemic heart disease (IHD), racial differences in counts of leukocyte subpopulations have received less attention.
We examined black/white differences in leukocyte subpopulations among 3467 white and 493 black 31-45 year-old-men who had previously served in the US Army.
Laboratory determinations were performed at a central location during 1985-1986.
Black men had an 840 cell/mul (or 15%) lower mean total leukocyte count than did white men, largely due to a 960 cell/mul (or 25%) lower mean neutrophil count.
Although black men also had a 20% lower mean monocyte count (=70 cells/mul) than did white men, their mean lymphocyte count was 10% higher (=200 cells/mul).
Counts of various leukocyte subpopulations were associated with cigarette smoking, haemoglobin levels, platelet counts, and several other characteristics, but black/white differences in counts of neutrophils, lymphocytes, monocytes and other subpopulations could not be attributed to any of the examined covariates.
Despite the relatively low counts of leukocytes and neutrophils among black men, their lymphocyte counts are generally higher than those among white men. (...)
Mots-clés Pascal : Infarctus, Myocarde, Leucocyte, Ethnie, Négroïde, Caucasoïde, Epidémiologie, Marqueur biologique, Prédiction, Homme, Etats Unis, Amérique du Nord, Amérique, Appareil circulatoire pathologie, Cardiopathie coronaire, Myocarde pathologie
Mots-clés Pascal anglais : Infarct, Myocardium, Leukocyte, Ethnic group, Negroid, Caucasoid, Epidemiology, Biological marker, Prediction, Human, United States, North America, America, Cardiovascular disease, Coronary heart disease, Myocardial disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0432818
Code Inist : 002B12A03. Création : 19/12/1997.